Table 3.

Cox proportions hazard regression of entire cohort, GG 1 group and GG 2 group predicting GG progression on subsequent biopsy

	Entire Cohort		Pos Fusion Biopsy		Neg Fusion Biopsy
	HR (95% CI)	p Value	HR (95% CI)	p Value	HR (95% CI)	p Value
Age/yr	1.05 (1.01–1.09)	0.03*	1.06 (1.01–1.10)	0.02*	1.04 (0.94–1.16)	0.43
PSA density	1.04 (1.01–1.07)	<0.01*	1.04 (1.01–1.07)	<0.01*	1.03 (0.96–1.11)	0.39
African American	1.31 (0.54–3.18)	0.55	2.60 (0.93–7.26)	0.07	0.56 (0.07–4.59)	0.59
In-house MRI suspicion score greater than moderate	0.40 (0.10–1.70)	0.22	0.42 (0.10–1.78)	0.24	–	–
No. MRI visible lesions	1.05 (0.83–1.34)	0.67	0.97 (0.74–1.26)	0.81	1.54 (0.77–3.06)	0.22
Largest lesion diameter	1.29 (0.73–2.28)	0.38	2.04 (1.12–3.72)	0.02*	0.27 (0.05–1.45)	0.13
Neg fusion biopsy	0.41 (0.22–0.77)	<0.01*	–	–	–	–

^*Statistically significant (p <0.05).