Table 1.
Patient demographic and clinical characteristics
| Characteristics (n = 13) | Value |
|---|---|
| Agea, median years (range) | 52.5 (6.8–60.9) |
| <18 | 1 (7.7) |
| 18–29 | 2 (15.4) |
| 30–39 | 1 (7.7) |
| 40–49 | 2 (15.4) |
| ≥ 50 | 7 (53.8) |
| Gender, n (%) | |
| Male | 10 (76.9) |
| Female | 3 (23.1) |
| Race and ethnicity, n (%) | |
| White non-Hispanic | 13 (100.0) |
| Region of residency, n (%) | |
| Midwestern United States | 6 (46.2) |
| Northeastern United States | 5 (38.5) |
| Southern United States | 1 (7.7) |
| Western United States | 1 (7.7) |
| Employment status, n (%)b | |
| Working | 4 (30.8) |
| Not working | 6 (46.2) |
| Student | 3 (23.1) |
| Marital status, n (%) | |
| Married | 7 (53.8) |
| Not marriedc | 4 (30.8) |
| ≤ 18 years old | 2 (15.4) |
| Months from transplant, median (range) | 52.6 (12.7–121.0) |
| Months from cGVHD diagnosis, median (range) | 39.1 (4.8–112.9) |
| Number of affected organs, median (range) | 5 (2–7) |
| Source of transplant, n (%) | |
| Peripheral blood stem cells | 11 (84.6) |
| Bone marrow | 2 (15.4) |
| HLA match, n (%) | |
| Matchd | 12 (92.3) |
| Mismatch | 1 (7.7) |
| Conditioning regimen, n (%) | |
| Myeloablative | 7 (53.8) |
| Reduced intensity | 1 (7.7) |
| Non-myeloablative | 5 (38.5) |
| Diagnosis, n (%) | |
| Leukemiae | 5 (30.8) |
| Lymphoma | 3 (23.1) |
| Multiple myeloma | 2 (15.4) |
| Myelodysplastic syndromes | 2 (15.4) |
| Polycythemia vera myelofibrosis | 1 (7.7) |
| History of acute GVHD, n (%) | |
| Yes | 9 (69.2) |
| No | 4 (30.8) |
Demographic and disease characteristics for the analytic sample at study enrollment
a
Age at the time of consent
b
“Working” includes individuals who work full or part time. “Not work-ing” includes individuals who are retired, unemployed, or serve as homemakers
c
Includes individuals who are divorced
d
Match defined as having a 6/6 or 10/10 HLA match with donor
e
Includes both chronic and acute leukemia