Table 4.
Relationship between changes in symptom burden, symptom severity, and measures of motor ability, function, and HRQOL
| Measures | Provider Global Rating |
Lee Symptom Scale |
||
|---|---|---|---|---|
| Correlation coefficient (ρ) | p value | Correlation coefficient (ρ) | p value | |
| Motor | ||||
| JTHFT | 0.082 | 0.789 | 0.194 | 0.526 |
| GPT | − 0.085 | 0.782 | 0.432 | 0.140 |
| Grip strength (lbs) | − 0.422 | 0.171 | − 0.438 | 0.154 |
| Pinch strength (lbs) | ||||
| Tip to tip | − 0.282 | 0.351 | − 0.214 | 0.482 |
| Palmar | − 0.332 | 0.268 | 0.438 | 0.134 |
| Key | 0.033 | 0.915 | − 0.612 | 0.026 |
| 2MWT (ft) | − 0.100 | 0.757 | − 0.357 | 0.255 |
| Functional | ||||
| AMPS | ||||
| ADL Motor skill | 0.409 | 0.166 | − 0.845 | < 0.001 |
| ADL Process skill | − 0.196 | 0.520 | − 0.057 | 0.853 |
| DASH | − 0.116 | 0.719 | 0.707 | 0.010 |
| HAP | ||||
| AAS | − 0.020 | 0.951 | − 0.248 | 0.437 |
| MAS | − 0.068 | 0.834 | 0.020 | 0.952 |
| MAM-36 | − 0.226 | 0.480 | − 0.103 | 0.751 |
| Quality of life | ||||
| SF-36 | ||||
| PCS | 0.306 | 0.334 | − 0.724 | 0.008 |
| MCS | − 0.342 | 0.276 | − 0.223 | 0.487 |
| Symptom severity | ||||
| Lee Symptom Scale | − 0.226 | 0.458 | ||
JTHFT, GPT, and pinch strength scores refer to performance with the dominant hand. Higher scores on the DASH, JTHFT, and GPT indicate poorer performance. Higher scores on the PGR and Lee Symptom Scale indicate greater symptom severity. Higher scores on all other measures indicate better performance. Italicized values indicate significant Spearman’s rank correlations between change scores (p ≤ 0.01)