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Framework to evaluate the temporal advantage of WBE versus clinical testing. The x-axis represents the onset of symptoms relative to the onset of RNA shedding in stool; the y-axis represents the differential in time to results between WBE and clinical testing. Indicated viral shedding areas are from (Hartman et al. 2020; Woolsey et al. 2021; Wölfel et al. 2020). The dashed green box indicates a representative plausible scenario range as discussed in the text.
