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. 2021 May 9;35(7):e23819. doi: 10.1002/jcla.23819

TABLE 2.

Correlation of circ_0015278 expression with PTC patients’ characteristics

Items Circ_0015278 expression
Q1 (1%−25%) (n = 52) Q2 (26%−50%) (n = 51) Q3 (51%−75%) (n = 52) Q4 (76%−100%) (n = 51) p Value
Age, no. (%)
<45 years 23 (44.2) 23 (45.1) 26 (50.0) 34 (66.7) 0.021
≥45 years 29 (55.8) 28 (54.9) 26 (50.0) 17 (33.3)
Gender, no. (%)
Male 12 (23.1) 17 (33.3) 11 (21.2) 10 (19.6) 0.404
Female 40 (76.9) 34 (66.7) 41 (78.8) 41 (80.4)
Tumor size, no. (%)
≤4 cm 31 (59.6) 30 (58.8) 32 (61.5) 38 (74.5) 0.117
>4 cm 21 (40.4) 21 (41.2) 20 (38.5) 13 (25.5)
Extrathyroidal invasion, no. (%)
Absent 25 (48.1) 29 (56.9) 34 (65.4) 34 (66.7) 0.036
Present 27 (51.9) 22 (43.1) 18 (34.6) 17 (33.3)
pT stage, no. (%)
pT1 9 (17.4) 2 (3.9) 7 (13.5) 11 (21.6) 0.005
pT2 5 (9.6) 20 (39.2) 18 (34.6) 19 (37.2)
pT3 19 (36.5) 13 (25.5) 12 (23.1) 11 (21.6)
pT4 19 (36.5) 16 (31.4) 15 (28.8) 10 (19.6)
pN stage, no. (%)
pN0 12 (23.1) 13 (25.5) 19 (36.5) 25 (49.0) 0.002
pN1 40 (76.9) 38 (74.5) 33 (63.5) 26 (51.0)
pTNM stage, no. (%)
I 25 (48.1) 23 (45.2) 27 (51.9) 36 (70.6) 0.001
II 1 (1.9) 4 (7.8) 5 (9.6) 6 (11.8)
III 15 (28.8) 15 (29.4) 8 (15.4) 9 (17.6)
IV 11 (21.2) 9 (17.6) 12 (23.1) 0 (0.0)

Abbreviations: pN, pathological node; pT, pathological tumor; PTC, papillary thyroid carcinoma; pTNM, pathological tumor‐node‐metastasis; Q1, quantile 1; Q2, quantile 2; Q3, quantile 3; Q4, quantile 4.