TABLE 4.
Cox's regression analysis of variables associated with OS.
| Parameters | Cox's proportional hazard regression model | |||
|---|---|---|---|---|
| p Value | HR | 95% CI | ||
| Lower | Higher | |||
| Univariate Cox's regression | ||||
| Higher circ_0015278 expression | 0.059 | 0.493 | 0.237 | 1.027 |
| Age (≥45 years vs. <45 years) | 0.092 | 6.074 | 0.747 | 49.398 |
| Gender (male vs. female) | 0.545 | 1.557 | 0.371 | 6.543 |
| Tumor size (>4 cm vs. ≤4 cm) | 0.012 | 14.835 | 1.815 | 121.243 |
| Extrathyroidal invasion (present vs. absent) | 0.057 | 4.751 | 0.953 | 23.682 |
| Higher pT stage | 0.040 | 2.546 | 1.043 | 6.216 |
| Higher pN stage | 0.188 | 4.091 | 0.502 | 33.325 |
| Higher pTNM stage | 0.029 | 2.081 | 1.080 | 4.009 |
| Adjuvant radioiodine therapy (yes vs. no) | 0.691 | 1.338 | 0.319 | 5.607 |
| Forward stepwise multivariate Cox's regression | ||||
| Tumor size (>4 cm vs. ≤4 cm) | 0.012 | 14.835 | 1.815 | 121.243 |
Abbreviations: CI, confidence interval; HR, hazards ratio; OS, overall survival; pN, pathological node; pT, pathological tumor; pTNM, pathological tumor‐node‐metastasis.