Table 4.
Patients | Anti-infective prescriptions | Antibiotic prescriptions, n (%) |
Antibiotic use guidelines available | |||||||
---|---|---|---|---|---|---|---|---|---|---|
Number | Based on biomarkera |
Reason in notes | Stop/ review date | Targeted treatmenta | ||||||
CRP | PCT | WBC | All | |||||||
Hospital 1 (n = 318) | 295 | 273 (92.5) | 0 | 0 | 4 (2.5) | 4 (2.5) | 165 (60.4) | 49 (17.9) | 1 (0.4) | none |
Hospital 2 (n = 150) | 154 | 140 (90.1) | 0 | 0 | 24 (15.4) | 24 (15.4) | 47 (33.6) | 79 (54.6) | 0 | none |
Hospital 3 (n = 122) | 148 | 137 (92.5) | 0 | 0 | 0 | 0 | 82 (59.9) | 103 (75.2) | 0 | none |
Hospital 4 (n = 140) | 193 | 161 (83.4) | 0 | 0 | 13 (82.9) | 13 (82.9) | 108 (67.1) | 113 (70.2) | 3 (1.9) | none |
Hospital 5 (n = 629) | 700 | 609 (87.0) | 0 | 0 | 37 (23.7) | 37 (23.7) | 314 (51.6) | 406 (66.7) | 10 (1.6) | none |
Hospital 6 (n = 988) | 967 | 890 (92.3) | 7 (0.8) | 6 (0.7) | 34 (21.8) | 46 (27.2) | 388 (43.6) | 201 (22.6) | 31 (3.5) | none |
Hospital 7 (n = 550) | 418 | 410 (98.1) | 0 | 0 | 44 (28.2) | 44 (26.0) | 158 (38.5) | 275 (67.1) | 8 (2.0) | none |
Total (n = 2897) | 2875 | 2620 (91.1) | 7 (0.5) | 6 (0.4) | 156 (11.4) | 169 (12.4) | 1262 (48.2) | 1226 (46.7) | 53 (3.9) | – |
Antibiotic prescriptions for systemic therapeutic use only (i.e., healthcare-associated or community-acquired infection, n = 1367); CRP, C-reactive protein; PCT, procalcitonin; WBC, white blood cells.