Table 1 –
Characteristics of incident RA cases and non-cases in licensed private pesticide applicators and spouses, Agricultural Health Study
| At enrollment | Non-cases N=48928 N (%) | Incident RA N=478 N (%) | OR (95%CI)1 |
|---|---|---|---|
| Age | |||
| < 40 | 14995 (31) | 93 (19) | Reference |
| 40–49 | 14721 (30) | 144 (30) | 1.58 (1.21 to 2.05) |
| 50–59 | 11495 (22) | 156 (33) | 2.19 (1.69 to 2.83) |
| 60+ | 7717 (16) | 85 (18) | 1.78 (1.32 to 2.39) |
| Participant type | |||
| Applicator | 26946 (55) | 229 (48) | Reference |
| Spouse | 21982 (45) | 249 (52) | 1.34 (1.12 to 1.61) |
| Sex2 | |||
| Male | 26246 (54) | 220 (46) | Reference |
| Female | 22682(46) | 258 (54) | 1.37 (1.14 to 1.64) |
| State | |||
| IA | 33782 (69) | 273 (57) | Reference |
| NC | 15146 (31) | 205 (43) | 1.58 (1.32 to 1.90) |
| Race/Ethnicity | |||
| White | 47691 (98) | 461 (96) | Reference |
| Other | 1195 (2.) | 17 (4) | 1.41 (0.86 to 2.29) |
| Education | |||
| <= High School | 24095 (49) | 267 (56) | Reference |
| > High School | 24833 (51) | 211 (44) | 0.85 (0.70 to 1.02) |
| Smoking status | |||
| Never Smoked | 32051 (66) | 273 (57) | Reference |
| Past Smoker | 11287 (23) | 120 (25) | 1.14 (0.92 to 1.42) |
| Current Smoker | 5516 (11) | 85 (18) | 1.86 (1.46 to 2.38) |
| Pack-years cigarettes | |||
| None | 32051 (65) | 273 (57) | Reference |
| <5 pack-years | 5969 (12) | 47 (10) | 0.93 (0.68 to 1.27) |
| 5–18 pack-years | 5675 (12) | 77 (16) | 1.54 (1.20 to 1.99) |
| > 18 pack-years | 5233 (11) | 81 (17) | 1.63 (1.27 to 2.11) |
1
Odds Ratios (OR) and 95% Confidence Intervals (CI), adjusting all other covariates by age.
2
Of the males, 112 non-cases and no cases were spouses; of the females, 812 non-cases and 9 cases were applicators.