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. 2021 Jul 5;13:5361–5372. doi: 10.2147/CMAR.S317631

Table 2.

Relationship Analyses Among PABPC1 Expression and Clinicopathologic Parameters in ESCC Tissues

Age Gender Smoking Alcohol Tumor Site Tumor Size DTCD LNM Pathological Type Pathological Stage Ki-67 PP p53 PP nm23 PP PABPC1 PP Outcome (Death) Tumor Recurrence
Age \ 0.091 −0.139 0.009 −0.054 −0.166 * 0.004 −0.13 −0.055 −0.051 0.035 0.113 −0.093 0.102 0.072 −0.052
Gender 0.091 \ −0.365** −0.361** −0.179** −0.02 0.008 −0.116 0.025 −0.07 0.106 0.024 0.112 0.061 −0.010 −0.024
Smoking −0.139 −0.365** \ 0.729** 0.01 0.045 −0.061 0.107 0.084 −0.026 −0.083 −0.18 * −0.067 −0.045 0.055 0.014
Alcohol 0.009 −0.361** 0.729** \ −0.043 0.005 −0.121 0.12 0.096 −0.009 −0.062 −0.066 −0.086 −0.105 0.206 * 0.14
Tumor site −0.054 −0.179** 0.010 −0.043 \ 0.197** 0.004 0.1 0 0.088 0.025 0.081 0.007 −0.075 −0.075 −0.061
Tumor size −0.166 * −0.020 0.045 0.005 0.197** \ 0.111 0.198** 0.007 0.241** 0.112 0.145 * −0.005 −0.049 0.072 0.174 *
DTCD 0.004 0.008 −0.061 −0.121 0.004 0.111 \ 0.273** −0.026 0.313** 0.215** 0.113 −0.0.103 0.124 0.152 0.204 *
LNM −0.13 −0.116 0.107 0.12 0.1 0.198** 0.273** 1 0.034 0.822** 0.139 * 0.061 −0.165 * 0.166 * 0.481** 0.499**
Pathological type −0.055 0.025 0.084 0.096 0 0.007 −0.026 0.034 \ 0.039 0.041 0.080 −0.013 0.076 0.007 −0.030
Pathological stage −0.051 −0.070 −0.026 −0.009 0.088 0.241** 0.313** 0.822** 0.039 \ 0.105 0.108 −0.139 * 0.136 * 0.504** 0.514**
Ki-67 PP 0.035 0.106 −0.083 −0.062 0.025 0.112 0.215** 0.139 * 0.041 0.105 \ −0.008 0.050 0.025 0.033 0.064
p53 PP 0.113 0.024 −0.18 * −0.066 0.081 0.145 * 0.113 0.061 0.08 0.108 −0.008 \ −0.133 * 0.001 0.017 −0.041
nm23 PP −0.093 0.112 −0.067 −0.086 0.007 −0.005 −0.0.103 −0.165 * −0.013 −0.139 * 0.05 −0.133 * \ −0.076 −0.100 −0.087
PABPC1 PP 0.102 0.061 −0.045 −0.105 −0.075 −0.049 0.124 0.166 * 0.076 0.136 * 0.025 0.001 −0.076 \ 0.384** 0.337**
Outcome (death) 0.072 −0.010 0.055 0.206 * −0.075 0.072 0.152 0.481** 0.007 0.504** 0.033 0.017 −0.100 0.384** \ 0.747**
Tumor recurrence −0.052 −0.024 0.014 0.14 −0.061 0.174 * 0.204 * 0.499** −0.03 0.514** 0.064 −0.041 −0.087 0.337** 0.747** \

Notes: Correlation between the parameters except “outcome” and “tumor recurrence” was based on the data from all the 231 patients. * at p<0.05 level, ** at p<0.01 level.

Abbreviations: ESCC, esophageal squamous cell carcinoma; DTCD, degree of tumor cell differentiation; LNM, lymph node metastasis; PP, percentage of positive tumor cells relative to the total number of tumor cells.