Table 1.
Basic and Clinical Features of the Training and Validation Sets in CKD Patients
| Total (n = 1452) |
Training Set (n =1022) |
Validation Set (n = 430) |
t/z/χ2 | P-value | |
|---|---|---|---|---|---|
| Age, n (%) | 54.4±14.4 | 54.9±14.1 | 53.3±14.9 | 1.954 | 0.051 |
| Male, n (%) | 874(60.2%) | 628(61.4%) | 246(57.2%) | 2.270 | 0.132 |
| CKD stage, n (%) | |||||
| stage 1–2 | 171(11.8%) | 130(12.7%) | 41(9.5%) | 3.345 | 0.341 |
| stage 3 | 261(18.0%) | 183(17.9%) | 78(18.1%) | ||
| stage 4 | 245(16.9%) | 174(17.0%) | 71(16.5%) | ||
| stage 5 | 775(53.4%) | 535(52.3%) | 240(55.8%) | ||
| Cardiovascular disease, n(%) | 499(34.4%) | 353(34.5%) | 146(34.0%) | 0.046 | 0.830 |
| Diabetes, n (%) | 380(26.2%) | 257(25.1%) | 123(28.6%) | 1.873 | 0.171 |
| Hypertension, n (%) | 1102(75.9%) | 769(75.2%) | 333(77.4%) | 0.799 | 0.371 |
| Smoking, n (%) | 447(30.8%) | 327(32.0%) | 120(27.9%) | 2.375 | 0.123 |
| Drinking, n (%) | 366(25.2%) | 258(25.2%) | 108(25.1%) | 0.003 | 0.959 |
| Body mass index, kg/m2 | 23.6±3.7 | 23.6±3.7 | 23.5±3.7 | 0.623 | 0.534 |
| Systolic blood pressure, mmHg | 142.0±24.8 | 142.0±24.9 | 142.1±24.7 | −0.078 | 0.938 |
| Uric acid, μmol/L | 426.6±131.3 | 426.5±131.0 | 427.7±130.7 | −0.158 | 0.875 |
| Serum hemoglobin, g/L | 101.1±26.4 | 101.4±26.3 | 100.5±26.7 | 0.551 | 0.582 |
| Albumin, g/L | 37.8(32.6–41.8) | 37.6(32.2–41.8) | 38.1(33.8–41.8) | −1.398 | 0.162 |
| Phosphorus, mmol/L | 1.43±0.50 | 1.42±0.49 | 1.46±0.51 | −1.291 | 0.197 |
| Calcium, mmol/L | 2.18(2.04–2.30) | 2.18(2.03–2.29) | 2.19(2.06–2.31) | −1.372 | 0.170 |
| Intact parathyroid hormone, pg/mL | 168.8(72.3–359.0) | 171.8(68.2–362.7) | 163.4(80.7–356.9) | −0.611 | 0.541 |
| Platelet counts, 109/L | 178.0(128.0–229.0) | 179.0(129.0–229.0) | 177.0(127.0–230.0) | −0.114 | 0.909 |
| Blood glucose, mmol/L | 4.69(4.21–5.47) | 4.66(4.20–5.40) | 4.78(4.25–5.65) | −1.721 | 0.085 |
| Urine total protein, g/24h | 1.94(0.67–4.06) | 2.00(0.67–4.13) | 1.85(0.68–3.89) | −0.621 | 0.535 |
| C-reactive protein, mg/L | 4.70(2.40–13.00) | 4.70(2.40–12.70) | 4.80(2.40–14.35) | −0.939 | 0.348 |
| Total cholesterol, mmol/L | 4.30(3.57–5.21) | 4.35(3.58–5.29) | 4.21(3.52–5.17) | −1.096 | 0.273 |
| Triglyceride, mmol/L | 1.51(1.08–2.14) | 1.51(1.08–2.16) | 1.52(1.07–2.09) | −0.114 | 0.909 |
| High density lipoprotein, mmol/L | 1.04(0.86–1.29) | 1.04(0.86–1.28) | 1.03(0.86–1.30) | −0.035 | 0.972 |
| Low density lipoprotein, mmol/L | 2.32(1.82–3.00) | 2.32(1.82–3.00) | 2.32(1.82–3.00) | −0.052 | 0.959 |
Notes: Uric acid: mg/dL=μmol/L×0.01681, Serum hemoglobin, g/dL=g/L×0.1, Albumin: g/dL=g/L×0.1, Phosphorus: mg/dL=mmol/L×3.097, Calcium: mg/dL=mmol/L×4.008, Intact parathyroid hormone: mg/dL=pg/mL, Platelet counts: mm3=109/L×1000, Blood glucose: mg/dL =mmol/L×18.02, C-reactive protein: mg/dL=mg/L×0.1, Total cholesterol: mg/dL=mmol/L×38.67, Triglyceride: mg/dL=mmol/L×88.545, High density lipoprotein: mg/dL=mmol/L×38.61, Low density lipoprotein: mmol/L mg/dL=mmol/L×38.61.
Abbreviations: CKD, chronic kidney disease; AS, atherosclerosis.