Table 4. Overall incidence of mumps-related complications [95% CI] during the study period in male and female mumps patients in a JMDC database cohort, according to age and sexa.
| Sex | Age group, years old |
Mumps-related complicationb | ||||||||||||||||||||
| All complications | Meningitis | Orchitis | Deafnessc | Pancreatitis | Encephalitis | Other complicationsd | ||||||||||||||||
| Mumps patients, n |
Onset patients, n |
Incidence [95% CI] |
Mumps patients, n |
Onset patients, n |
Incidence [95% CI] |
Mumps patients, n |
Onset patients, n |
Incidence [95% CI] |
Mumps patients, n |
Onset patients, n |
Incidence [95% CI] |
Mumps patients, n |
Onset patients, n |
Incidence [95% CI] |
Mumps patients, n |
Onset patients, n |
Incidence [95% CI] |
Mumps patients, n |
Onset patients, n |
Incidence [95% CI] |
||
| All | All ages | 68,280 | 787 | 11.5 [10.7–12.4] |
68,290 | 398 | 5.8 [5.3–6.4] |
36,519 | 242 | 6.6 [5.8–7.5] |
68,137 | 88 | 1.3 [1.0–1.6] |
68,307 | 32 | 0.5 [0.3–0.7] |
68,307 | 22 | 0.3 [0.2–0.5] |
68,307 | 25 | 0.4 [0.2–0.5] |
| 0–5 | 26,050 | 132 | 5.1 [4.2–6.0] |
26,050 | 110 | 4.2 [3.5–5.1] |
14,231 | 2 | 0.1 [0.0–0.5] |
26,013 | 7 | 0.3 [0.1–0.6] |
26,056 | 6 | 0.2 [0.1–0.5] |
26,056 | 5 | 0.2 [0.1–0.4] |
26,056 | 2 | 0.1 [0.0–0.3] |
|
| 6–15 | 35,684 | 332 | 9.3 [8.3–10.4] |
35,684 | 227 | 6.4 [5.6–7.2] |
19,036 | 32 | 1.7 [1.2–2.4] |
35,590 | 38 | 1.1 [0.8–1.5] |
35,693 | 13 | 0.4 [0.2–0.6] |
35,693 | 14 | 0.4 [0.2–0.7] |
35,693 | 10 | 0.3 [0.1–0.5] |
|
| 16–25 | 1,529 | 60 | 39.2 [30.1–50.2] |
1,531 | 13 | 8.5 [4.5–14.5] |
701 | 35 | 49.9 [35.0–68.8] |
1,523 | 8 | 5.3 [2.3–10.3] |
1,531 | 3 | 2.0 [0.4–5.7] |
1,531 | 1 | 0.7 [0.0–3.6] |
1,531 | 3 | 2.0 [0.4–5.7] |
|
| 26–35 | 2,412 | 147 | 60.9 [51.7–71.2] |
2,414 | 26 | 10.8 [7.0–15.7] |
1,158 | 100 | 86.4 [70.8–104.0] |
2,411 | 17 | 7.1 [4.1–11.3] |
2,416 | 5 | 2.1 [0.7–4.8] |
2,416 | 2 | 0.8 [0.1–3.0] |
2,416 | 6 | 2.5 [0.9–5.4] |
|
| 36–45 | 1,898 | 85 | 44.8 [35.9–55.1] |
1,904 | 19 | 10.0 [6.0–15.5] |
972 | 55 | 56.6 [42.9–73.0] |
1,896 | 8 | 4.2 [1.8–8.3] |
1,904 | 5 | 2.6 [0.9–6.1] |
1,904 | 0 | 0.0 [0.0–1.9] |
1,904 | 3 | 1.6 [0.3–4.6] |
|
| 46–55 | 549 | 25 | 45.5 [29.7–66.5] |
549 | 3 | 5.5 [1.1–15.9] |
345 | 15 | 43.5 [24.5–70.7] |
546 | 7 | 12.8 [5.2–26.2] |
549 | 0 | 0.0 [0.0–6.7] |
549 | 0 | 0.0 [0.0–6.7] |
549 | 1 | 1.8 [0.0–10.1] |
|
| 56–64 | 158 | 6 | 38.0 [14.1–80.8] |
158 | 0 | 0.0 [0.0–23.1] |
76 | 3 | 39.5 [8.2–111.1] |
158 | 3 | 19.0 [3.9–54.5] |
158 | 0 | 0.0 [0.0–23.1] |
158 | 0 | 0.0 [0.0–23.1] |
158 | 0 | 0.0 [0.0–23.1] |
|
| Male | All ages | 36,507 | 581 | 15.9 [14.7–17.3] |
36,517 | 260 | 7.1 [6.3–8.0] |
36,519 | 242 | 6.6 [5.8–7.5] |
36,432 | 51 | 1.4 [1.0–1.8] |
36,529 | 21 | 0.6 [0.4–0.9] |
36,529 | 10 | 0.3 [0.1–0.5] |
36,529 | 16 | 0.4 [0.3–0.7] |
| 0–5 | 14,228 | 80 | 5.6 [4.5–7.0] |
14,228 | 66 | 4.6 [3.6–5.9] |
14,231 | 2 | 0.1 [0.0–0.5] |
14,206 | 3 | 0.2 [0.0–0.6] |
14,231 | 6 | 0.4 [0.2–0.9] |
14,231 | 1 | 0.1 [0.0–0.4] |
14,231 | 2 | 0.1 [0.0–0.5] |
|
| 6–15 | 19,029 | 227 | 11.9 [10.4–13.6] |
19,029 | 155 | 8.1 [6.9–9.5] |
19,036 | 32 | 1.7 [1.2–2.4] |
18,978 | 22 | 1.2 [0.7–1.8] |
19,036 | 8 | 0.4 [0.2–0.8] |
19,036 | 6 | 0.3 [0.1–0.7] |
19,036 | 6 | 0.3 [0.1–0.7] |
|
| 16–25 | 701 | 49 | 69.9 [52.2–91.4] |
703 | 7 | 10.0 [4.0–20.4] |
701 | 35 | 49.9 [35.0–68.8] |
697 | 5 | 7.2 [2.3–16.7] |
703 | 2 | 2.8 [0.3–10.2] |
703 | 1 | 1.4 [0.0–7.9] |
703 | 2 | 2.8 [0.3–10.2] |
|
| 26–35 | 1,156 | 124 | 107.3 [90.0–126.5] |
1,158 | 17 | 14.7 [8.6–23.4] |
1,158 | 100 | 86.4 [70.8–104.0] |
1,159 | 7 | 6.0 [2.4–12.4] |
1,160 | 3 | 2.6 [0.5–7.5] |
1,160 | 2 | 1.7 [0.2–6.2] |
1,160 | 4 | 3.4 [0.9–8.8] |
|
| 36–45 | 972 | 72 | 74.1 [58.4–92.4] |
978 | 12 | 12.3 [6.4–21.3] |
972 | 55 | 56.6 [42.9–73.0] |
974 | 6 | 6.2 [2.3–13.4] |
978 | 2 | 2.0 [0.2–7.4] |
978 | 0 | 0.0 [0.0–3.8] |
978 | 1 | 1.0 [0.0–5.7] |
|
| 46–55 | 345 | 23 | 66.7 [42.7–98.4] |
345 | 3 | 8.7 [1.8–25.2] |
345 | 15 | 43.5 [24.5–70.7] |
342 | 5 | 14.6 [4.8–33.8] |
345 | 0 | 0.0 [0.0–10.6] |
345 | 0 | 0.0 [0.0–10.6] |
345 | 1 | 2.9 [0.1–16.0] |
|
| 56–64 | 76 | 6 | 78.9 [29.5–164.0] |
76 | 0 | 0.0 [0.0–47.4] |
76 | 3 | 39.5 [8.2–111.1] |
76 | 3 | 39.5 [8.2–111.1] |
76 | 0 | 0.0 [0.0–47.4] |
76 | 0 | 0.0 [0.0–47.4] |
76 | 0 | 0.0 [0.0–47.4] |
|
| Female | All ages | 31,773 | 206 | 6.5 [5.6–7.4] |
31,773 | 138 | 4.3 [3.7–5.1] |
na | na | na | 31,705 | 37 | 1.2 [0.8–1.6] |
31,778 | 11 | 0.3 [0.2–0.6] |
31,778 | 12 | 0.4 [0.2–0.7] |
31,778 | 9 | 0.3 [0.1–0.5] |
| 0–5 | 11,822 | 52 | 4.4 [3.3–5.8] |
11,822 | 44 | 3.7 [2.7–5.0] |
na | na | na | 11,807 | 4 | 0.3 [0.1–0.9] |
11,825 | 0 | 0.0 [0.0–0.3] |
11,825 | 4 | 0.3 [0.1–0.9] |
11,825 | 0 | 0.0 [0.0–0.3] |
|
| 6–15 | 16,655 | 105 | 6.3 [5.2–7.6] |
16,655 | 72 | 4.3 [3.4–5.4] |
na | na | na | 16,612 | 16 | 1.0 [0.6–1.6] |
16,657 | 5 | 0.3 [0.1–0.7] |
16,657 | 8 | 0.5 [0.2–0.9] |
16,657 | 4 | 0.2 [0.1–0.6] |
|
| 16–25 | 828 | 11 | 13.3 [6.6–23.6] |
828 | 6 | 7.2 [2.7–15.7] |
na | na | na | 826 | 3 | 3.6 [0.7–10.6] |
828 | 1 | 1.2 [0.0–6.7] |
828 | 0 | 0.0 [0.0–4.4] |
828 | 1 | 1.2 [0.0–6.7] |
|
| 26–35 | 1,256 | 23 | 18.3 [11.6–27.4] |
1,256 | 9 | 7.2 [3.3–13.6] |
na | na | na | 1,252 | 10 | 8.0 [3.8–14.6] |
1,256 | 2 | 1.6 [0.2–5.7] |
1,256 | 0 | 0.0 [0.0–2.9] |
1,256 | 2 | 1.6 [0.2–5.7] |
|
| 36–45 | 926 | 13 | 14.0 [7.5–23.9] |
926 | 7 | 7.6 [3.0–15.5] |
na | na | na | 922 | 2 | 2.2 [0.3–7.8] |
926 | 3 | 3.2 [0.7–9.4] |
926 | 0 | 0.0 [0.0–4.0] |
926 | 2 | 2.2 [0.3–7.8] |
|
| 46–55 | 204 | 2 | 9.8 [1.2–35.0] |
204 | 0 | 0.0 [0.0–17.9] |
na | na | na | 204 | 2 | 9.8 [1.2–35.0] |
204 | 0 | 0.0 [0.0–17.9] |
204 | 0 | 0.0 [0.0–17.9] |
204 | 0 | 0.0 [0.0–17.9] |
|
| 56–64 | 82 | 0 | 0.0 [0.0–44.0] |
82 | 0 | 0.0 [0.0–44.0] |
na | na | na | 82 | 0 | 0.0 [0.0–44.0] |
82 | 0 | 0.0 [0.0–44.0] |
82 | 0 | 0.0 [0.0–44.0] |
82 | 0 | 0.0 [0.0–44.0] |
|
aBased on health insurance claims data from JMDC Inc.
bIncidence per 1,000 mumps cases, respectively.
cDocumented diagnosis of mumps deafness.
dIncludes: arthritis, myocarditis, nephritis, polyneuropathy, hepatitis, and oophoritis.
na; not analyzable.