Fig. 11.

Filaments of the PYRIN domain of fully protonated mouse ASC. a 1D-hcH spectrum and structural model of ASC filaments (PDB 2N1F) (Sborgi et al. 2015), b one-dimensional trace at δ₁(¹³C) = 42.06 ppm of c, c, d 2D hCH spectra and e expanded regions from the spectra in c, d. Spectra colored in blue were recorded at 850 MHz and spectra in red were measured at 1200 MHz