Table 1.

Genome-wide significant single nucleotide polymorphisms (SNPs) for natural log-transformed 25(OH)D levels and their association with ADHD

SNP		25(OH)D						ADHD					Palindromic + ambiguous
		A1	A2	Eaf (A1)	Beta	SE	P value	A1	A2	OR	SE	P value
rs10741657	CYP2R1	A	G	0.40	0.031	0.0022	2.05E–46	A	G	1.0048	0.0137	0.728	False
rs10745742	AMDHD1	T	C	0.40	0.017	0.0022	1.88E–14	T	C	1.0141	0.0138	0.311	False
rs12785878	NADSYN1-DHCR7	T	G	0.75	0.036	0.0022	3.80E–62	T	G	1.0313	0.0146	0.035	False
rs17216707a	CYP24A1	T	C	0.77	0.026	0.0027	8.14E–23
ars209955		T	C	0.31b	− 0.019	0.0024	2.49E−16	T	C	1.003	0.0156	0.848	False
rs3755967	GC	T	C	0.28	− 0.089	0.0023	4.74E–343	T	C	1.0235	0.015	0.122	False
rs8018720	SEC23A	C	G	0.82	− 0.017	0.0029	4.72E–09	C	G	0.9958	0.0185	0.819	True

Eaf effect allele frequency, OR odds ratio, SE standard error, palindromic + ambiguous true this SNP is palindromic and ambiguous and will be excluded

^ars209955 is the proxy for rs17216707: distance = − 9491, D′ = 0.7908, r² = 0.4115; A1: Allele 1; A2: Allele 2

^bEaf (European) from https://ldlink.nci.nih.gov/?tab=ldhap