Table 2.
Oxidative stress biomarkers in liver of rainbow trout treated with tributyltin chloride (TBTC) and tributyltin ethoxide (TBTE)
| Days | CRT | TBTC 0.05 mg/kg | TBTC 0.5 mg/kg | TBTE 0.05 mg/kg | TBTE 0.5 mg/kg | |
|---|---|---|---|---|---|---|
| MDA | 3 | 16.41 ± 6.88c | 22.69 ± 5.01bc | 28.68 ± 6.33b | 27.39 ± 8.40b | 47.03 ± 8.56a |
| 6 | 20.90 ± 8.76b | 27.89 ± 8.04b | 24.78 ± 2.13b | 26.57 ± 3.29b | 41.07 ± 7.94a | |
| GSH+2GSSG | 3 | 1339.78 ± 376.54a | 1652.02 ± 397.69a | 1663.85 ± 227.50a | 1429.44 ± 227.24a | 1223.65 ± 268.53a |
| 6 | 1303.85 ± 235.29a | 1236.43 ± 204.65a | 878.74 ± 97.94a | 1248.91 ± 101.26a | 1160.61 ± 162.17a | |
| SOD | 3 | 15.05 ± 1.99a | 16.50 ± 3.13a | 15.24 ± 3.13a | 12.91 ± 1.47a | 15.61 ± 1.74a |
| 6 | 12.70 ± 2.94a | 11.58 ± 3.13ac | 7.05 ± 1.70b | 10.28 ± 1.49ab | 7.59 ± 1.55bc | |
| CAT | 3 | 156.03 ± 26.78c | 219.29 ± 18.31a | 259.16 ± 50.04a | 83.01 ± 10.83b | 112.56 ± 28.15bc |
| 6 | 170.13 ± 13.66a | 175.10 ± 26.14a | 167.22 ± 33.44a | 143.67 ± 28.86a | 160.31 ± 10.31a | |
| GPx | 3 | 25.28 ± 4.33b | 39.75 ± 2.80a | 40.04 ± 9.82a | 26.13 ± 3.50b | 33.54 ± 8.44ab |
| 6 | 29.47 ± 8.23b | 35.30 ± 9.10b | 51.67 ± 6.52a | 34.78 ± 8.65b | 32.12 ± 8.69b | |
| GST | 3 | 136.41 ± 11.98c | 123.32 ± 8.36bc | 188.62 ± 18.00a | 107.59 ± 20.34bc | 87.07 ± 5.95b |
| 6 | 153.50 ± 23.04a | 139.06 ± 17.30a | 124.17 ± 27.06a | 146.95 ± 27.08a | 155.59 ± 24.91a |
Liver of each group was analysed individually. Data are reported as mean and standard deviation. Different letters (a, b, c) indicate statistically significant differences (p<0.05) between control and treated groups (TBTC or TBTE) at the same time point
MDA malondialdehyde, GSH+2GSSG total glutathione, SOD superoxide dismutase, CAT catalase, GPx glutathione peroxidase, GST glutathione S-transferase, CRT control