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. 2021 Jul 12;12:4251. doi: 10.1038/s41467-021-24524-8

Fig. 5. Time course of dyskinesia after gene transfer.

Fig. 5

Dyskinesia score, adapted from the Abnormal Involuntary Movement Scale (AIMS). Involuntary movements in each of 7 body regions were scored from 0 (none) to 4 (severe), for a maximum possible score of 28. A total score of 14 (dotted line) may correspond with either mild generalized dyskinesia, or moderate-severe involuntary movements in a more focal distribution. Dyskinesia peaked in severity between 1 and 3 months after surgery, and gradually improved thereafter. At Month 24, dyskinesia had resolved completely in all 3 subjects in Cohort 1.