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. Author manuscript; available in PMC: 2023 Feb 1.
Published in final edited form as: Clin Gastroenterol Hepatol. 2021 Jan 14;20(2):e64–e73. doi: 10.1016/j.cgh.2020.12.021

Table 1.

Demographic and Clinical Characteristics of Sample

N = 3976

Age in years 52.9 (16.2)

Male Gender 40.4% (1121)

Chicago Classification 3.0 Diagnosis
Disorders of EGJ Outflow Obstruction 30.4% (797)
 Achalasia I 4.2% (110)
 Achalasia II 5.0% (131)
 Achalasia III 3.5% (92)
 EGJOO 17.7% (464)
Major Motor Disorders 12.5% (328)
 Absent Contractility 9.1% (238)
 Jackhammer Esophagus 1.6% (41)
 Distal Esophageal Spasm 1.9% (49)
Minor Disorders of Peristalsis 17.6% (462)
 Fragmented Peristalsis 1.2% (31)
 Ineffective Esophageal Motility 16.4% (431)
Normal Esophageal Motility 39.4% (1031)

Other Esophageal Disorders 34.2% (1358)
 GERD 12.9% (511)
 Prior Foregut Surgery 18.8% (747)

Eosinophilic Esophagitis 12.9% (109)

Diagnostic Tests
 High Resolution Manometry 84.6% (3365)
  FLIP 22.6% (898)

Indication for Evaluation
 Dysphagia 49.1% (1528)
 Heartburn/Reflux 24.0% (745)
 Chest pain 6.5% (202)
 Pre-Operative 7.7% (240)
 Follow-Up 12.7% (395)

On PPI Therapy 64.4% (1227)

Notes: 1906 patients had any PPI use in the registry.