Table 2.
Cox regression-factors affecting OS and NRM in all the patients (MC and CC).
| N = 217 patients | OS | NRM | ||||
|---|---|---|---|---|---|---|
| HR (UV/MV) | CI (UV/MV) | P (UV/MV) | HR (UV/MV) | CI (UV/MV) | P (UV/MV) | |
| Conditioning regimen (ref RIC) | 1.2 | 0.8–1.83 | 0.21 | 1.7/1.9 | 0.9–3.1/1.07–3.5 | 0.07/0.06 |
| Disease risk (DRI, ref low risk) | 1.3 | 0.8–1.9 | 0.24 | 1.2 | 0.6–2.3 | 0.60 |
| Age (ref < 52) | 1.89/1.7 | 1.3–2.9/1.1–2.6 | 0.001/0.013 | 2.4 /2.7 | 1.3–5.2/1.3–5.7 | 0.03/0.04 |
| Matching (ref 9/10) | 0.60/0.65 | 0.4–0.8/0.43–0.9 | 0.02/0.019 | 0.65 | 0.3–1.2 | 0.20 |
| MC vs CC (ref MC) | 1.53/1.5 | 1.0–2.2/1.05–2.2 | 0.04/0.02 | 1.9/1.9 | 1.3–3.5/1.0–3.2 | 0.05/0.02 |
OS overall survival, DFS disease-free survival, NRM non-relapse mortality, MA myeloablative regimen, RIC reduced-intensity conditioning, MC mixed chimerism, CC complete chimerism, pDLI pre-emptive donor lymphocyte infusion, NA not applicable.