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. 2021 Jul 12;11:14283. doi: 10.1038/s41598-021-93742-3

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© The Author(s) 2021, corrected publication 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Jitter boxplots comparing HML6_3p21.31c expression between ALS and controls across seven post-mortem RNA-sequence datasets. We found increased expression of HML6_3p21.31c in all motor cortex and cerebellum cohorts, but not in the frontal cortex tissue. X-axes: Disease status. Y-axes: Normalised expression of HML6_3p21.31c. Dots: HML6_3p21.31c expression for each sample. Boxplot: Boxplot of the distribution of HML6_3p21.31c. Boxplot colour: Disease status (ALS: Red; Control: Blue). Figure titles: Data source and tissue. Log2 FC: Log2 Fold-change, SE: Standard error, p value: Derived from differential expression analysis.