Table 3.

Co-expression analyses using post-mortem motor cortex tissue from the KCL cohort.

HML6.3p21.31c co-expresses with genes in the yellow network-module. This network-module positively correlated with ALS disease status, in concordance with increased expression of HML6.3p21.31c in ALS compared to controls. In this network-module, HML6.3p21.31c was the most significantly differentially expressed region (which includes ERVs and genes).

N Genes: Number of genes in the module; Genes up/down regulation in ALS (p < 0.05): Number of genes in the module that show differential expression comparing ALS and controls with a p value < 0.05.