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. 2021 Jul 12;11:14278. doi: 10.1038/s41598-021-93468-2

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Differential metabolites between infected resistant and susceptible ponies (day 132). Panel (A) shows metabolite signal intensity distribution in each pony susceptibility group (purple: resistant, TR; green: susceptible, TS) at day 132. Panel (B) shows the relationship between these metabolite signal intensities (Y-axis) at day 0, and matching log-transformed faecal egg count (X-axis) at day 132. Panel (C) describes observed phenylalanine levels in the faecal matter of an independent cohort of British horses with low or high FEC.