Table 2.

Fold difference in kidney RAS gene expression in Lewis rats after RDN.

Gene	ΔΔCt			Fold difference v. sham (range)		P value
	Sham RDN	Total RDN	Afferent RDN	Total RDN	Afferent RDN
Renin	0.0 ± 0.7	0.1 ± 0.7	0.8 ± 0.8	0.92 (0.56–1.51)	0.59 (0.33–1.05)	0.75
AGT	0.0 ± 1.1	− 0.6 ± 1.2	-0.9 ± 1.1	1.51 (0.65–3.50)	1.81 (0.87–3.76)	0.86
ACE1	0.0 ± 0.6	− 0.5 ± 0.6	0.1 ± 0.4	1.46 (0.9–2.24)	0.92 (0.72–1.19)	0.68
ACE2	0.0 ± 0.3	− 0.5 ± 0.3	-0.5 ± 0.4	1.38 (1.10–1.73)	1.45 (1.10–1.92)	0.50
Agtr1a	0.0 ± 0.2	0.1 ± 0.2	− 0.1 ± 0.2	0.93 (0.82–1.06)	1.05 (0.91–1.22)	0.84

RAS renin-angiotensin system, AGT angiotensinogen, ACE angiotensin-converting enzyme, Agtr1a angiotensin type 1a receptor. Data are presented as ΔΔCt with the sham animals used as the reference group. Fold difference (range) was calculated using the 2^{−(ΔΔCt ± Standard Error (SE) of the ΔCt)} method.