Table 3.

Fold difference in kidney RAS gene expression in Lewis Polycystic Kidney (LPK) rats after RDN.

Gene	ΔΔCt			Fold difference vs. sham (range)		P value
	Sham RDN	Total RDN	Afferent RDN	Total RDN	Afferent RDN
Renin	0.0 ± 0.2	− 0.3 ± 0.2	− 0.3 ± 0.5	1.27 (1.10–1.46)	1.19 (0.81–1.75)	0.84
AGT	0.0 ± 0.6	0.6 ± 0.4	− 1.0 ± 0.5	0.67 (0.51–0.87)	2.07 (1.49–2.87)	0.10
ACE1	0.0 ± 0.1	0.2 ± 0.2	0.4 ± 0.4	0.87 (0.75–1.02)	0.74 (0.56–0.99)	0.64
ACE2	0.0 ± 0.4	− 0.1 ± 0.2	− 1.0 ± 0.5	1.07 (0.95–1.20)	2.00 (1.43–2.82)	0.20
Agtr1a	0.0 ± 0.3	− 1.0 ± 0.4	− 0.3 ± 0.5	1.98 (1.47–2.65)	1.22 (0.89–1.68)	0.25

RAS renin-angiotensin system, AGT angiotensinogen, ACE angiotensin-converting enzyme, Agtr1a angiotensin type 1a receptor. Data are presented as ΔΔCt with the sham animals used as the reference group. Fold difference (range) was calculated using the 2^{−(ΔΔCt ± Standard Error (SE) of the ΔCt)} method.