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. 2021 Jul 12;11:14269. doi: 10.1038/s41598-021-93774-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Distribution of the mean intra-subject differences between QTc intervals by different correction formulas and the corresponding QTcI values. The distribution of the differences is shown for calculations over all study time-points (top left panel), time-points with stable heart rate (bottom left panel), morning fasting time-points (top right panel), and morning fasting time-points with stable heart rate (bottom right panel). The layout of the panels and the meaning of the box and whisker graphs is the same as in Fig. 8. ms milliseconds.