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. 2021 Jun 29;12:627533. doi: 10.3389/fphar.2021.627533

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Copyright © 2021 Seiwerth, Milavic, Vukojevic, Gojkovic, Krezic, Vuletic, Pavlov, Petrovic, Sikiric, Vranes, Prtoric, Zizek, Durasin, Dobric, Staresinic, Strbe, Knezevic, Sola, Kokot, Sever, Lovric, Skrtic, Blagaic and Sikiric.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Total debridement of corneal epithelium and BPC 157 therapy (Lazic et al., 2005). Total debridement of corneal epithelium preformed in rats unilaterally and lesions stained (green) and photographed. Medication was distilled water (control group) or BPC 157 2 pg/ml, 2 ng/ml, and 2 μg/ml, two drops/rat eye started immediately after injury induction, every 8 h up to 40 h (i.e., at 0, 8, 16, 24, 32, and 40 h). Lesions presentation at 24 h in controls (C) and lesions attenuation in BPC 157 rats (B), lesions presentation at 32 h in controls (C) and lesions disappearance in BPC 157 rats (B).