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. 2021 Jun 29;12:627533. doi: 10.3389/fphar.2021.627533

FIGURE 2.

FIGURE 2

Excisional wound in diabetic rats (0, 1) and in rats with ligation of the right iliac artery and vein (2) (upper) and BPC 157 therapy (lower). At 3 days before wounding, alloxan (300 mg/kg sc), thin layer of the BPC 157 cream (1 µg/1 g neutral cream) (white number), or neutral cream (black number) was immediately given upon wounding (0, 0). Advanced wound healing presentation at 24 h in BPC 157 rats (1, white), but not in controls (1, black). Likewise, advanced healing in the rats with ligated right iliac arteries and veins, when ingested BPC 157 through drinking water (10 μg/kg, 10 ng/kg, 0.16 μg/ml, 0.16 ng/ml, and 12 ml/rat/day) at postsurgery day 4 (2, white), but not in controls (2, black).