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. 2021 Jul 13;5(4):zraa048. doi: 10.1093/bjsopen/zraa048

Table 4.

Univariable and multivariable logistic regression analyses of risk factors for grade B or C posthepatectomy liver failure

No. of patients Univariable analysis
Multivariable analysis
Odds ratio P Odds ratio P
rHUI *
 < 0·410 18 6·4 × 103 (77·9, 1·1 ×108) < 0·001 2·0 × 103 (19·6, 3·8 × 107) < 0·001
 ≥ 0·410 49 1·00 (reference) 1·00 (reference)
Total bilirubin (mg/dl) *
 > 0·83 20 5·85 (1·08, 31·66) 0·026 34·4 (0·5, 9·7 ×103) 0·070
 ≤ 0·83 47 1·00 (reference) 1·00 (reference)
Serum albumin (g/dl) *
 < 3·4 14 2·61 (0·54, 12·63) 0·247
 ≥ 3·4 53 1·00 (reference)
Prothrombin time (%) *
 < 80 11 7·42 (1·50, 36·60) 0·016 33·2 (0·5, 7·3 × 103) 0·070
 ≥ 80 56 1·00 (reference) 1·00 (reference)
ICGK *
 < 0·171 26 5·85 (1·08, 31·66) 0·026 60·0 (0·4, 4·8 × 104) 0·081
 ≥ 0·171 41 1·00 (reference) 1·00 (reference)
ICGK-F *
 < 0·08 26 14·1 (1·69, 128·46) 0·002
 ≥ 0·08 41 1·00 (reference)
FLR volume (ml) *
 < 407 16 14·7 (2·58, 83·65) < 0·001
 ≥ 407 51 1·00 (reference)
FLR proportion (%) *
 < 42 25 15·9 (1·82, 139·27) 0·001
 ≥ 42 42 1·00 (reference)

Values in parentheses are 95 per cent confidence intervals.

*

Cut-off values were determined to minimize the value of the Youden index. rHUI, remnant hepatocellular uptake index; ICGK, plasma clearance rate of indocyanine green (ICG); ICGK-F, future liver remnant (FLR) plasma clearance rate of ICG.