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. 2006 Jan 25;2006(1):CD004257. doi: 10.1002/14651858.CD004257.pub2

3. Number needed to harm ‐ GI events Acetaminophen vs NSAIDs.

Intervention % w NSAID % w Acetaminophen RR (95%CI) ARD(95%CI) NNH (95% CI)
Traditional NSAID 91/484 (19%) 51/407(13%) 1.47 (1.08,2.00) 6%(1%, 11%) 12 (6,66)
Coxib NSAIDs 303/2320 (13%) 118/994(12%) 0.98(0.80, 1.20) 0%(‐1%, 4%) NA
Combined traditional & Coxib 394/2804(14%) 169/1401 (12%) 1.11 (0.94, 1.31) 1%(‐1%,3%) NA
Legend ARD=absolute risk difference 
 NA=not applicable 
 
 ARD=Absolute risk difference 
 NA=not applicable