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Guanylate cyclase C (GC-C) is expressed in neurons of different brain regions. GC-C (green) co-localized with a neuronal nuclei marker (NeuN = red, left panel) but not with the astrocytes marker, glial fibrillary acidic protein (GFAP = red, right panel) in (A) the hypothalamus, (B) cerebellar cortex, (C) cerebellar deep nuclei, and (D) cerebral cortex of wild-type mice. GC-C knockout (KO) mice were used as a negative control. Bar represents 50 μm.
