TABLE 1.

D-dimer Assays and Assay-Specific Results

D-dimer Assay	Units	Linear Range	ULN	Upper Limit of Linear Assay Detection/ULN	No. of Patients	No. of Sites	Median (IQR) Fold-Difference From ULN
Stago STA Liatest	ng/mL FEU	270–4,000	500	8.0	1,111	21	4.7 (2.7–8.0)
HemosIL HS	ng/mL D-dimer units	150–3,680	243	15.1	769	13	3.3 (1.7–10.6)
Siemans Innovance	ng/mL FEU	120–4,460	500	8.9	723	11	3.3 (1.7–8.3)
HemosIL HS500	ng/mL FEU	215–7,650	500	15.3	542	16	3.4 (1.8–10.2)
bioMérieux Vidas	ng/mL FEU	45–10,000	500	20.0	151	3	2.6 (1.7–4.9)
Roche Tina-quant	ng/mL FEU	150–9,000	500	18.0	122	2	3.5 (1.8–10.3)

FEU = fibrinogen equivalence units, IQR = interquartile range, ULN = upper limit of normal defined as the assay manufacturer specified venous thromboembolism cutoff.