Table 1.

Commonly up-regulated proteins changes of M1 polarization in both the THP-1 and RAW264.7 cell models determined by global proteomics and PRM.

Gene Name	Global Proteomics fold change				PRM fold change
	PMA-THP-1s		RAW264.7		PMA-THP-1s		RAW264.7
	M1/M0	M2/M0	M1/M0	M2/M0	M1/M0	M2/M0	M1/M0	M2/M0
CMPK2	4.27	0.37	20.94	0.72	5.99	0.30	16.38	0.55
RSAD2	10.29	1.00	4.91	0.68	65.89	0.96	304.22	2.09
DDX58	6.17	0.57	3.05	0.83	5.02	0.37	2.79	0.73
DHX58	2.38	0.68	3.17	0.90	12.93	0.03	2.06	0.96
CEBPB	4.12	1.29	3.13	0.70	6.56	2.09	10.71	0.35
GBP4	5.54	0.65	10.06	0.87	30.10	0.23	38.59	0.35
IFI44L	5.87	0.01	3.50	0.63	46.26	2.01	2.54	0.48
IFIT1	7.43	0.57	12.91	0.94	5.90	0.15	292.01	0.45
IL1B	2.56	0.15	5.48	1.28	6.17	0.03	163.97	2.75
LGALS3BP	2.12	0.55	2.37	0.63	7.65	0.76	2.41	0.46
NT5C3A	3.58	0.55	6.21	0.99	4.02	0.78	2.30	0.73
PLAUR	4.50	2.25	32.36	0.74	4.35	1.93	18.74	0.62
PML	3.78	0.67	2.44	1.03	4.39	0.82	2.32	0.74
PTGS2	100.00	100.00	30.77	0.78	413.83	53.66	150.38	1.39
SLC15A3	100.00	100.00	8.90	0.91	2.91	1.71	229.08	5.01
SLFN5	3.52	1.89	6.96	1.07	4.66	1.69	4.72	0.64