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. 2021 Jun 29;11:592927. doi: 10.3389/fonc.2021.592927

Table 4.

Risk stratification model for thyroid nodules > 4 cm.

Patterns Points Risk value No. malignant nodules (malignancy rate, %)
training dataset (n = 29) Validation dataset (n = 21)
High risk 9 (90.0) 8 (88.9)
 More than 3 factors 190-290 0.8-0.9
Intermediate risk 8 (42.1) 5 (35.7)
 2 factors 120-170 0.4-0.7
 Microcalcification 100 0.34
Low risk 12 (10.8) 8 (6.9)
 Solid 70 0.21
 Ill-defined border 70 0.21
 Hypoechoic 50 0.14

The four significant factors were microcalcification, solid, ill-defined border, and hypoechoic.