Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jun 29;12:669150. doi: 10.3389/fimmu.2021.669150

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Wu, Wang, Zheng, Qiu, Wang and Chen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

The interaction between gut microbiota and immune system (1). Bacteroides fragilis takes advantage of IgA to settle down in the intestine of mice (2); SFB induces the appearance of CD4+ T helper cells in lamina propria (3); Clusters IV and XIVa of the genus Clostridium are associated with Tregs accumulation in colon (4); SCFAs regulate Foxp3 in Tregs, inhibit immune response of T cells (5); SCFAs induce expressing of IL-10 and Aldh1a1 in DCs, result in inhibiting the development of Th17 cell (6); Polysaccharide A secreted by Bacteroides fragilis binds to TLR2 in Tregs, enhances Tregs and suppresses the proinflammatory Th17 response.