Table 1. The IC50 of JCo extract and VP-16 in HCC and normal cells.
| JCo extract (μg/ml) | VP-16 (μg/ml) | ||||||
|---|---|---|---|---|---|---|---|
| Cell line | Tumor type | 24 h | 48 h | 72 h | 24 h | 48 h | 72 h |
| HCC cells | |||||||
| Mahlavu | Human HCC | 64.9 ± 3.11,2 | 58.5 ± 2.31,2 | 59.4 ± 1.01,2 | 54.7 ± 7.0 | 5.5 ± 0.8 | <6.25 |
| HepG2 | Human HCC | 48.9 ± 1.51,2 | 42.3 ± 0.21,2 | 43.9 ± 2.61,2 | >200 | 18.1 ± 2.8 | <6.25 |
| J5 | Human HCC | 74.2 ± 3.61,2 | 67.2 ± 2.01,2 | 53.2 ± 31,2 | >200 | 14.1 ± 0.9 | 7.3 ± 2.7 |
| Normal cells | |||||||
| MDCK | Canis kidney epithelial cell | >87.7 | >87.7 | 84.0 ± 0.6 | >50 | 25.7 ± 2.7 | 2.7 ± 0.2 |
| SEVC | Mouse vascular endothelia cell | 78.8 ± 0.4 | 67.4 ± 0.4 | 66.8 ± 0.05 | 21.7 ± 4.9 | 1.9 ± 0.06 | 1.8 ± 0.1 |
Values are reported as mean ± SD (μg/ml). It was significantly different that compared HCC cells with MDCK (1) or SVEC (2) in JCo extract treatment at the same time points (P<0.05).