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. 2021 Jul 12;41(7):BSR20211143. doi: 10.1042/BSR20211143

Table 1. The IC50 of JCo extract and VP-16 in HCC and normal cells.

JCo extract (μg/ml) VP-16 (μg/ml)
Cell line Tumor type 24 h 48 h 72 h 24 h 48 h 72 h
HCC cells
Mahlavu Human HCC 64.9 ± 3.11,2 58.5 ± 2.31,2 59.4 ± 1.01,2 54.7 ± 7.0 5.5 ± 0.8 <6.25
HepG2 Human HCC 48.9 ± 1.51,2 42.3 ± 0.21,2 43.9 ± 2.61,2 >200 18.1 ± 2.8 <6.25
J5 Human HCC 74.2 ± 3.61,2 67.2 ± 2.01,2 53.2 ± 31,2 >200 14.1 ± 0.9 7.3 ± 2.7
Normal cells
MDCK Canis kidney epithelial cell >87.7 >87.7 84.0 ± 0.6 >50 25.7 ± 2.7 2.7 ± 0.2
SEVC Mouse vascular endothelia cell 78.8 ± 0.4 67.4 ± 0.4 66.8 ± 0.05 21.7 ± 4.9 1.9 ± 0.06 1.8 ± 0.1

Values are reported as mean ± SD (μg/ml). It was significantly different that compared HCC cells with MDCK (1) or SVEC (2) in JCo extract treatment at the same time points (P<0.05).