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. 2021 Jun 29;11:699781. doi: 10.3389/fonc.2021.699781

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Copyright © 2021 Liu, Luo, Yi, Zeng and Tan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Deterministic Sensitivity Analysis. The red solid line represents the willingness-to-pay threshold of $100,000 used this analysis. The black dotted line represents the incremental cost-effectiveness ratio (ICER) between alternatives under comparison. The top 10 most influential parameters of the ICERs are displayed. AEP indicated atezolizumab combined with etoposide and platinum; DEP, durvalumab combined with etoposide and platinum; QALY, quality adjusted life year; ICER, incremental cost-effectiveness ratio; AE, adverse event; PFS, progression-free survival; PS, progressed survival.