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. 2021 Jun 29;11:671327. doi: 10.3389/fonc.2021.671327

Table 4.

Results and adverse events within included studies for ablation.

Investigators Follow-up (mo) (range) Technical success Technical effectiveness PFS (EG or EG vs CG) Median OS (EG or EG vs CG) Adverse events (grade III/IV)
Carrafiello (75) Mean 17.5 (13–21) / 66 / / None
Kim (76) Median 19.5 (3.3–82.1) 88% 88% 32.2 mo 38.5 mo Liver abscess (n = 1)
Giorgi (77) Median 19.5 (9-64) / 66 / / None
Yu (87) Mean 12.8 (4–31) 91.70% 87.50% / 10 mo Liver abscess (13.3%), needle seeding (6.7%)
Zhang (88) Median 20.1 (2.8–63.5) 100% 93.00% 8.9 mo (95% CI,6.5–11.3) 28 mo (95% CI, 23.7–32.2) Pleural effusion (1.9%), liver abscess (0.9%)
Xu (89) / 100 vs 100% 100 vs 100% P = 0.589 31.3 vs 29.4, P = 0.405 MWA: hepatic failure (n = 1), liver abscesses (n = 2), ascites (n = 1)
SR: hepatic failure (n = 2), ascites (n = 6), jaundice (n = 3)
MWA vs SR: 5.3 vs 13.8% (P < 0.001)
Belfiore (98) (6–48) 100% 100% / 18 mo (95% CI, 18.8–36.7) None

PFS, progression-free survival; OS, overall survival; MWA, microwave ablation; SR, surgical resection; CG, control group; EG, experimental group.