| Methods |
Active comparator controlled randomized trial; double blinded. |
| Participants |
90 patients presenting at a university hospital emergency department with an acute arthritis clinically "suggestive of gout". |
| Interventions |
44 patients (male 35) received a systematic corticosteroid: 30mg oral prednisolone daily for 5 days. 46 (male 39) patients received indomethacine (IDM) 50mg TID for 2 days and 25mg TID for 3 days after 1 initial intramuscular injection with 75mg diclofenac (control therapy). In both treatment arms additional paracetamol 1000mg every 4 hours as required. |
| Outcomes |
Pain reduction at rest, as with activity, scored on a visual analogue scale of 10cm. |
| Notes |
7 patients, all from the IDM group, had to stop the study medication because of adverse effects. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment? |
Low risk |
A ‐ Adequate |
