Table 1.
Summary of the role of AQP9 in susceptibility to Plasmodium infection according to the different cell types and plasmodial species tested on the basis of RNA silencing experiments.
| Human | Mouse | ||||
|---|---|---|---|---|---|
| Human hepatocytes (CD81+/AQP9+) | HepG2 (CD81-/AQP9-) | HepG2/CD81(CD81+/AQP9-) | HepaRG(CD81+/AQP9+) | Mouse hepatocytes (CD81+/AQP9+) | |
| P. falciparum | AQP9-dependent | no infection | no infection | infection (role of AQP9 not tested) | no infection |
| P. yoelii | AQP9-independent | no infection | AQP9-independent | infection (role of AQP9 not tested) | AQP9-independent |
| P. berghei | AQP9-dependent | AQP9-independent | AQP9-independent | AQP9-dependent | AQP9-dependent |