Table 4.
Distribution of non-motor symptoms in idiopathic Parkinson's Disease blocking for “enrollment age” (percentiles).
|
<62 y.o. <25% (n = 368) |
62–69 y.o. 25–50% (n = 376) |
69–75 y.o. 50–75%(n = 392) |
≥75 y.o. ≥75% (n = 453) |
|
|---|---|---|---|---|
| Patients with at least one NMS | 317 (86.1%) | 335 (89.1%) | 351 (89.5%) | 403 (89%) |
| Non-motor symptoms | ||||
| Attention disorders | 41 (11.1%) | 40 (10.6%) | 62 (15.8%) | 61 (13.5%) |
| Cardiovascular symptoms | 20 (5.4%) | 32 (8.5%) | 41 (10.5%) | 57 (12.6%) |
| Cognitive symptoms | 37 (10.1%) | 57 (15.2%) | 67 (17.1%) | 105 (23.2%) |
| Fatigue | 83 (22.6%) | 97 (25.8%) | 104 (26.5%) | 121 (26.7%) |
| Gastrointestinal symptoms | 66 (17.9%) | 83 (22.1%) | 108 (27.6%) | 119 (26.3%) |
| Pain | 73 (19.8%) | 85 (22.6%) | 84 (21.4%) | 90 (19.9%) |
| Primary sensory symptoms | 28 (7.6%) | 39 (10.4%) | 30 (7.7%) | 28 (6.2%) |
| Psychiatric symptoms | 164 (44.6%) | 159 (42.3%) | 173 (44.1%) | 188 (41.5%) |
| Respiratory symptoms | 4 (1.1%) | 8 (2.1%) | 8 (2%) | 11 (2.4%) |
| Skin disorders | 8 (2.2%) | 8 (2.1%) | 11 (2.8%) | 10 (2.2%) |
| Sleep disorders | 162 (44%) | 174 (46.3%) | 188 (48%) | 196 (43.3%) |
| Urinary symptoms | 59 (16%) | 84 (22.3%) | 98 (25%) | 110 (24.3%) |
| Other non-motor symptoms | 38 (10.3%) | 47 (12.5%) | 34 (8.7%) | 43 (9.5%) |
| Missing information | 3 (0.8%) | 4 (1.1%) | 3 (0.8%) | 3 (0.7%) |