Table 5.
Distribution of non-motor symptoms in idiopathic Parkinson's disease blocking for “years from diagnosis” (percentiles).
|
<4 y. <25% (n = 338) |
4–7 y. 25%–50% (n = 421) |
7–11 y. 50%–75% (n = 411) |
≥ 11 y. ≥ 75% (n = 419) |
|
|---|---|---|---|---|
| Patients with at least one NMS | 289 (85.5%) | 371 (88.1%) | 360 (87.6%) | 386 (92.1%) |
| Non-motor symptoms | ||||
| Attention disorders | 32 (9.5%) | 60 (14.3%) | 50 (12.2%) | 62 (14.8%) |
| Cardiovascular symptoms | 32 (9.5%) | 33 (7.8%) | 41 (10%) | 44 (10.5%) |
| Cognitive symptoms | 45 (13.3%) | 65 (15.4%) | 69 (16.8%) | 87 (20.8%) |
| Fatigue | 74 (21.9%) | 120 (28.5%) | 92 (22.4%) | 119 (28.4%) |
| Gastrointestinal symptoms | 71 (21%) | 100 (23.8%) | 102 (24.8%) | 103 (24.6%) |
| Pain | 66 (19.5%) | 85 (20.2%) | 78 (19%) | 103 (24.6%) |
| Primary sensory symptoms | 20 (5.9%) | 24 (5.7%) | 34 (8.3%) | 47 (11.2%) |
| Psychiatric symptoms | 130 (38.5%) | 177 (42%) | 174 (42.3%) | 203 (48.4%) |
| Respiratory symptoms | 2 (0.6%) | 9 (2.1%) | 6 (1.5%) | 14 (3.3%) |
| Skin disorders | 4 (1.2%) | 13 (3.1%) | 6 (1.5%) | 14 (3.3%) |
| Sleep disorders | 159 (47%) | 175 (41.6%) | 184 (44.8%) | 202 (48.2%) |
| Urinary symptoms | 56 (16.6%) | 82 (19.5%) | 94 (22.9%) | 119 (28.4%) |
| Other non-motor symptoms | 44 (13%) | 50 (11.9%) | 35 (8.5%) | 33 (7.9%) |
| Missing information | 3 (0.9%) | 8 (1.9%) | 1 (0.2%) | 1 (0.2%) |