Table 3.

Risk of bias assessment (observational studies)—TE events, major bleeding, all bleeding events and mortality

	Bias due to confounding	Bias in selection of participants	Bias in classification of interventions	Bias due to deviations from intended interventions	Bias due to missing data	Bias in measurement of outcomes	Bias in selection of reported result	Overall risk of bias
Martinelli et al29	Serious risk	Low risk	Moderate risk	Low risk	Low risk	Serious risk (except for mortality—low)	Serious risk (except for mortality—low)	Serious risk
Malec et al30	Serious risk	Serious risk	Low risk	Low risk	Serious risk	Serious risk (except for mortality—low)	Moderate risk (except for mortality—low)	Serious risk
Sato et al31	Moderate risk	Moderate risk	Serious risk	Low risk	Low risk	Serious risk (except for mortality—low)	Serious risk (except for mortality —low)	Serious risk

TE, thromboembolism.