Table 3.
Genotype and allele frequency for the rs2144300 and rs4846914 SNPs of the GALNT2 gene in women with GDM and control subjects divided into overweight/obese and nonobese subgroups.
| GDM | Control | |||||
|---|---|---|---|---|---|---|
| Overweight/Obese (n = 330) | Non-obese (n = 131) | p | Overweight/Obese (n = 452) | Non-obese (n = 174) | p | |
| rs2144300 | ||||||
| Genotype | 0.455 | 0.934 | ||||
| CC | 68.5% (226) | 61.6% (82) | 65.9% (298) | 67.2% (117) | ||
| CT | 29.4% (97) | 34.3% (45) | 29.7% (134) | 28.2% (49) | ||
| TT | 2.1% (7) | 3.1% (4) | 4.4% (20) | 4.6% (8) | ||
| Allele | 0.222 | 0.818 | ||||
| C | 83.2% (549) | 79.8% (209) | 80.8% (731) | 81.3% (283) | ||
| T | 16.8% (111) | 20.2% (53) | 19.2% (174) | 18.7% (65) | ||
| rs4846914 | ||||||
| Genotype | 0.774 | 0.611 | ||||
| GG | 57.9% (197) | 56.5% (74) | 58.0% (262) | 59.8% (104) | ||
| GA | 33.3% (110) | 35.1% (46) | 35.6% (161) | 32.2% (56) | ||
| AA | 7.0% (23) | 8.4% (11) | 6.4% (29) | 8.0% (14) | ||
| Allele | 0.459 | 0.974 | ||||
| G | 76.4% (504) | 74.0% (194) | 75.8% (685) | 75.9% (264) | ||
| A | 23.6% (156) | 26.0% (68) | 24.2% (219) | 24.1% (84) | ||
Numbers in parentheses indicate number of subjects with each genotype or number of alleles of each type.