Figure 5.

An example of the wound healing course of a PRESTIGE enrolled patient. The patient presented with a 2-month history of a worsening left heel wound with a long occlusion of the left anterior tibial artery (ATA) and disease within the left dorsalis pedis artery (A). There was minor disease within the left peroneal artery (PA). The posterior tibial artery was completely occluded with no target vessel to aim for distally. Decision to open the left ATA. Once the chronic total occlusion (CTO) was crossed from an antegrade position, the lesion was prepared with 3 mm × 240 mm (proximally) and 2.5 mm × 80 mm (distally) high-pressure noncompliant plain balloons (Jade, OrbusNeich, Hong Kong) each for a duration of 3 minutes. Selution SLR DEB (drug-eluting balloon) (3 mm × 150 mm ×2 and 2.5 mm × 150 mm) were then applied to cover the whole lesion length from origin of ATA to DPA each for 2-minute duration to allow maximal drug transfer to the arterial wall. The PA was predilated with a 3-mm high-pressure noncompliant balloon and drugged with a 3 mm × 150 mm Selution SLR DEB. No slow phenomenon was noticed on the angiogram run afterward in either vessel. (B) The 6-month arterial duplex scan showing patency of both the ATA and PA each with a biphasic signal. (C) The wound healing course of the heel ulcer, which had completely healed by 3 months and had stayed closed at the 6-month follow up.