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. 2004 Jul 19;2004(3):CD003470. doi: 10.1002/14651858.CD003470.pub2

Darracott 1973.

Methods RCT, double blind, method of randomisation not specified 
 Low quality: Delphi score 3
Participants 43 military patients with severe unilateral painful patella, fulfilling diagnostic criteria of chondromalacia patellae 
 40 male, 3 female 
 Age 17‐34 (mean 22, SD 4) 
 Duration of symptoms 4 ‐ 36 months, onset due to trauma in 12 patients, to surgery in 11, to patellar subluxation, 2 to severe exercise, 1 to kneeling and 16 spontaneous
Interventions All patients performed gradually increasing exercises to reverse quadriceps inhibition for 6‐8 weeks until return to full circuit and battle training, combined with:
(1) Intramuscular administration of nandrolone phenylpropionate 25 mg weekly for 6 weeks (anabolic ester in arachis oil) (n=23)
(2) Intramuscular administration of placebo weekly for 6 weeks (arachis oil) (n=20)
Outcomes Subjective change in clinical symptoms 
 Change in bone density in skyline radiographs (using healthy knee for calibration)
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear