Darracott 1973.
Methods | RCT, double blind, method of randomisation not specified Low quality: Delphi score 3 | |
Participants | 43 military patients with severe unilateral painful patella, fulfilling diagnostic criteria of chondromalacia patellae 40 male, 3 female Age 17‐34 (mean 22, SD 4) Duration of symptoms 4 ‐ 36 months, onset due to trauma in 12 patients, to surgery in 11, to patellar subluxation, 2 to severe exercise, 1 to kneeling and 16 spontaneous | |
Interventions | All patients performed gradually increasing exercises to reverse quadriceps inhibition for 6‐8 weeks until return to full circuit and battle training, combined with: (1) Intramuscular administration of nandrolone phenylpropionate 25 mg weekly for 6 weeks (anabolic ester in arachis oil) (n=23) (2) Intramuscular administration of placebo weekly for 6 weeks (arachis oil) (n=20) |
|
Outcomes | Subjective change in clinical symptoms Change in bone density in skyline radiographs (using healthy knee for calibration) | |
Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |