Table 5.
GO annotation of upregulated proteins in broiler chickens in the immune stress group
| GO ID | GO Term | Term P- value | Associated proteins enriched |
|---|---|---|---|
| Biological process | |||
| GO:0009617 | Response to bacterium | 81.0E-9 | AvBD1, AvBD2, AvBD7, CATH2, CATH3, CD36, FGB, LY86, LYN, RSFR, TAP2 |
| GO:0098542 | Defense response to other organism | 1.4E-6 | AvBD1, AvBD2, AvBD7, CATH2, CATH3, CD36, FADD, FGB, OASL, RSFR |
| GO:0042742 | Defense response to bacterium | 87.0E-9 | AvBD1, AvBD2, AvBD7, CATH2, CATH3, CD36, FGB, RSFR |
| GO:0050829 | Defense response to Gram-negative bacterium | 33.0E-6 | AvBD7, CATH2, CATH3, RSFR |
| GO:0050829 | Defense response to Gram-positive bacterium | 79.0E-6 | CATH2, CATH3, CD36, RSFR |
| GO:0016054 | Organic acid catabolic process | 3.3E-3 | AGXT2, HIBCH, OAT, SLC27A4 |
| GO:0009063 | Cellular amino acid catabolic process | 3.3E-3 | AGXT2, HIBCH, OAT |
| GO:0046395 | Carboxylic acid catabolic process | 3.3E-3 | AGXT2, HIBCH, OAT, SLC27A4 |
| GO:1901606 | Alpha-amino acid catabolic process | 2.4E-3 | AGXT2, HIBCH, OAT |
| GO:0051279 | Regulation of release of sequestered calcium ion into cytosol | 1.5E-3 | CLIC2, LYN, SRI |
| GO:0097553 | Calcium ion transmembrane import into cytosol | 5.6E-3 | CLIC2, LYN, SRI |
| GO:0032845 | Negative regulation of homeostatic process | 2.1E-3 | CLIC2, FADD, LYN, SRI |
| GO:0051238 | Sequestering of metal ion | 8.4E-3 | CLIC2, LYN, SRI |
| GO:0032387 | Negative regulation of intracellular transport | 10.0E-3 | CD36, CLIC2, SRI |
| GO:1903650 | Negative regulation of cytoplasmic transport | 5.3E-3 | CD36, CLIC2, SRI |
| GO:0051282 | Regulation of sequestering of calcium ion | 5.6E-3 | CLIC2, LYN, SRI |
| GO:0051208 | Sequestering of calcium ion | 5.9E-3 | CLIC2, LYN, SRI |
| GO:0051283 | Negative regulation of sequestering of calcium ion | 5.6E-3 | CLIC2, LYN, SRI |
| GO:0090279 | Regulation of calcium ion import | 3.5E-3 | CLIC2, LYN, SRI |
| GO:0010522 | Regulation of calcium ion transport into cytosol | 2.2E-3 | CLIC2, LYN, SRI |
| GO:1903169 | Regulation of calcium ion transmembrane transport | 3.7E-3 | CLIC2, LYN, SRI |
| GO:0060402 | Calcium ion transport into cytosol | 8.0E-3 | CLIC2, LYN, SRI |
| GO:0051209 | Release of sequestered calcium ion into cytosol | 5.6E-3 | CLIC2, LYN, SRI |
| GO:1902656 | Calcium ion import into cytosol | 6.2E-3 | CLIC2, LYN, SRI |
| GO:0050818 | Regulation of coagulation | 460.0E-6 | CD36, FGB, FGG, LYN |
| GO:0072376 | Protein activation cascade | 1.2E-3 | C4, FGB, FGG |
| GO:0007599 | Hemostasis | 970.0E-6 | CD36, FGA, FGB, FGG, LYN |
| GO:1900046 | Regulation of hemostasis | 320.0E-6 | CD36, FGB, FGG, LYN |
| GO:0007596 | Blood coagulation | 930.0E-6 | CD36, FGA, FGB, FGG, LYN |
| GO:0030168 | Platelet activation | 590.0E-6 | FGA, FGB, FGG, LYN |
| GO:0071219 | Cellular response to molecule of bacterial origin | 10.0E-3 | CD36, LY86, LYN |
| GO:0030193 | Regulation of blood coagulation | 320.0E-6 | CD36, FGB, FGG, LYN |
| GO:0061041 | Regulation of wound healing | 1.4E-3 | CD36, FGB, FGG, LYN |
| GO:0070527 | Platelet aggregation | 1.2E-3 | FGB, FGG, LYN |
| GO:0071222 | Cellular response to LPS | 9.8E-3 | CD36, LY86, LYN |
| GO:0002793 | Positive regulation of peptide secretion | 1.8E-3 | FGB, FGG, SRI |
| GO:0046887 | Positive regulation of hormone secretion | 5.6E-3 | FGB, FGG, SRI |
| GO:0008625 | Extrinsic apoptotic signaling pathway via death domain receptors | 250.0E-6 | FADD, FGB, FGG, STK4 |
| GO:1904019 | Epithelial cell apoptotic process | 4.8E-3 | FGB, FGG, STK4 |
| GO:0090277 | Positive regulation of peptide hormone secretion | 1.8E-3 | FGB, FGG, SRI |
| GO:1902041 | Regulation of extrinsic apoptotic signaling pathway via death domain receptors | 63.0E-6 | FADD, FGB, FGG, STK4 |
| Pathway | |||
| GO:0000280 | Valine, leucine and isoleucine degradation | 3.1E-3 | AGXT2, HIBCH, IL4I1 |