Table 2.
Adjusted mean differences in RSMS total scores between the genetic groups stratified by global CDR® plus NACC FTLD scores, with 95% bias-corrected confidence intervals. Significant values are shown in bold
| C9ORF72 | GRN | MAPT | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 | 0.5 | 1+ | 0 | 0.5 | 1+ | 0 | 0.5 | 1+ | |||||||||||
| Controls | −0.91 | −5.34 | −22.39 | −0.35 | −4.05 | −17.41 | 1.99 | 2.07 | −24.28 | ||||||||||
| −3.41 | 1.60 | −9.36 | -1.32 | −25.72 | −19.05 | −2.17 | 1.47 | −8.53 | 0.42 | −20.94 | −13.88 | −1.21 | 5.19 | −5.72 | 9.86 | −32.48 | −16.08 | ||
| C9ORF72 | 0 | −4.43 | −21.48 | 0.55 | −3.15 | −16.50 | 2.90 | 2.97 | −23.37 | ||||||||||
| −9.10 | 0.24 | −25.68 | −17.29 | −2.29 | 3.39 | −8.19 | 1.90 | −20.84 | −12.17 | −0.91 | 6.71 | −5.02 | 10.97 | −31.89 | −14.86 | ||||
| 0.5 | −17.05 | 4.99 | 1.29 | −12.07 | 7.33 | 7.41 | −18.94 | ||||||||||||
| −21.93 | −12.16 | 0.61 | 9.36 | −4.54 | 7.11 | −17.17 | −6.98 | 2.19 | 12.48 | −1.18 | 15.99 | −27.88 | −10.01 | ||||||
| 1+ | 22.04 | 18.34 | 4.98 | 24.38 | 24.45 | −1.89 | |||||||||||||
| 18.41 | 25.66 | 12.93 | 23.74 | 0.40 | 9.55 | 19.79 | 28.97 | 16.28 | 32.63 | −10.40 | 6.61 | ||||||||
| GRN | 0 | −3.70 | −17.06 | 2.35 | 2.42 | −23.93 | |||||||||||||
| −8.60 | 1.20 | −20.77 | −13.35 | −1.31 | 6.00 | −5.61 | 10.44 | −32.26 | −15.60 | ||||||||||
| 0.5 | −13.36 | 6.05 | 6.12 | −20.23 | |||||||||||||||
| −18.76 | −7.96 | 0.72 | 11.38 | −2.59 | 14.83 | −29.17 | −11.29 | ||||||||||||
| 1+ | 19.41 | 19.48 | −6.87 | ||||||||||||||||
| 14.54 | 24.27 | 11.10 | 27.85 | −15.59 | 1.85 | ||||||||||||||
| MAPT | 0 | 0.07 | −26.27 | ||||||||||||||||
| −7.46 | 7.60 | −35.02 | −17.53 | ||||||||||||||||
| 0.5 | −26.35 | ||||||||||||||||||
| −36.96 | −15.74 | ||||||||||||||||||
| 1+ | |||||||||||||||||||