Table 2.
Association of UI and clinicopathological features of PTC
| Variables | Urinary iodine, μg/L | |||
|---|---|---|---|---|
| n (%) | Low (%) | High (%) | P value | |
| n = 181 | n = 178 | |||
| Age | ||||
| ≥ 45 | 155 (43.2) | 82 (22.8) | 73 (20.3) | 0.273 |
| < 45 | 204 (56.8) | 96 (26.7) | 108 (30.1) | |
| Sex | ||||
| Male | 104 (29) | 48 (13.4) | 56 (15.6) | 0.407 |
| Female | 255 (71) | 130 (36.2) | 125 (34.8) | |
| BMI, kg/m2 | ||||
| ≥ 24 | 205 (57.1) | 109 (30.4) | 96 (26.7) | 0.117 |
| < 24 | 154 (42.9) | 69 (19.2) | 85 (23.7) | |
| Diabetes | ||||
| Yes | 16 (4.5) | 9 (2.5) | 7 (1.9) | 0.585 |
| No | 343 (95.5) | 169 (47.1) | 174 (48.5) | |
| Hypertension | ||||
| Yes | 63 (17.5) | 37 (10.3) | 26 (7.2) | 0.11 |
| No | 296 (82.5) | 141 (39.3) | 155 (43.2) | |
| Tobacco use | ||||
| Yes | 38 (10.6) | 19 (5.3) | 19 (5.3) | 0.957 |
| No | 321 (89.4) | 159 (44.3) | 162 (45.1) | |
| Tumor size | ||||
| ≥ 1 cm | 125 (34.8) | 64 (17.8) | 61 (17) | 0.654 |
| < 1 cm | 234 (65.2) | 114 (31.8) | 120 (33.4) | |
| Multifocality | ||||
| Yes | 131 (36.5) | 60 (16.7) | 71 (19.8) | 0.277 |
| No | 228 (63.5) | 118 (32.9) | 110 (30.6) | |
| Capsular invasion | ||||
| Yes | 253 (70.5) | 129 (35.9) | 124 (34.5) | 0.41 |
| No | 106 (29.5) | 49 (13.6) | 57 (15.9) | |
| Nodular goiter | ||||
| Yes | 99 (27.6) | 52 (14.5) | 47 (13.1) | 0.491 |
| No | 260 (72.4) | 126 (35.1) | 134 (37.3) | |
| Chronic thyroiditis | ||||
| Yes | 94 (26.2) | 50 (13.9) | 44 (12.3) | 0.415 |
| No | 265 (73.8) | 128 (35.7) | 137 (38.2) | |
| Thyroid adenoma | ||||
| Yes | 5 (1.4) | 3 (0.8) | 2 (0.6) | 0.683 |
| No | 354 (98.6) | 175 (48.7) | 179 (49.9) | |
| Variant subtype | ||||
| Classic | 261 (72.7) | 127 (35.4) | 134 (37.3) | 0.173 |
| Follicular | 65 (18.1) | 38 (10.6) | 27 (7.5) | |
| Classic and follicular (multiple foci) | 33 (9.2) | 13 (3.6) | 20 (5.6) | |
| CLNM | ||||
| Yes | 166 (46.2) | 71 (19.8) | 95 (26.5) | 0.017 |
| No | 193 (53.8) | 107 (29.8) | 86 (24) | |