Table 3.
Correlation of UI/U-Cr and clinicopathological features of PTC
| Variables | Before PSM | After PSM | ||||||
|---|---|---|---|---|---|---|---|---|
| n | UI/U-Cr, μg/g | P value | n | UI/U-Cr, μg/g | P value | |||
| Low | High | Low | High | |||||
| n = 176 | n = 183 | n = 118 | n = 118 | |||||
| Age | ||||||||
| ≥ 45 | 155 (43.2) | 60 (16.7) | 95 (26.5) | 0.001 | 105 (44.5) | 49 (20.8) | 56 (23.7) | 0.359 |
| < 45 | 204 (56.8) | 116 (32.3) | 88 (24.5) | 131 (55.5) | 69 (29.2) | 62 (26.3) | ||
| Sex | ||||||||
| Male | 104 (29) | 63 (17.5) | 41 (11.4) | 0.005 | 59 (25) | 27 (11.4) | 32 (13.6) | 0.452 |
| Female | 255 (71) | 113 (31.5) | 142 (39.6) | 177 (75) | 91 (38.6) | 86 (36.4) | ||
| BMI, kg/m2 | ||||||||
| ≥ 24 | 205 (57.1) | 105 (29.2) | 100 (27.9) | 0.337 | 130 (55.1) | 67 (28.4) | 63 (26.7) | 0.601 |
| < 24 | 154 (42.9) | 71 (19.8) | 83 (23.1) | 106 (44.9) | 51 (21.6) | 55 (23.3) | ||
| Diabetes | ||||||||
| Yes | 16 (4.5) | 3 (0.8) | 13 (3.6) | 0.013 | 10 (4.2) | 2 (0.8) | 8 (3.4) | 0.102 |
| No | 343 (95.5) | 173 (48.2) | 170 (47.4) | 226 (95.8) | 116 (49.2) | 110 (46.6) | ||
| Hypertension | ||||||||
| Yes | 63 (17.5) | 29 (8.1) | 34 (9.5) | 0.601 | 41 (17.4) | 19 (8.1) | 22 (9.3) | 0.606 |
| No | 296 (82.5) | 147 (40.9) | 149 (41.5) | 195 (82.6) | 99 (41.9) | 96 (40.7) | ||
| Tobacco use | ||||||||
| Yes | 38 (10.6) | 21 (5.8) | 17 (4.7) | 0.416 | 25 (10.6) | 12 (5.1) | 13 (5.5) | 0.832 |
| No | 321 (89.4) | 155 (43.2) | 166 (46.2) | 211 (89.4) | 106 (44.9) | 105 (44.5) | ||
| Tumor size | ||||||||
| ≥ 1 cm | 125 (34.8) | 55 (15.3) | 70 (19.5) | 0.164 | 88 (37.3) | 40 (16.9) | 48 (20.3) | 0.282 |
| < 1 cm | 234 (65.2) | 121 (33.7) | 113 (31.5) | 148 (62.7) | 78 (33.1) | 70 (29.7) | ||
| Multifocality | ||||||||
| Yes | 131 (36.5) | 57 (15.9) | 74 (20.6) | 0.113 | 93 (39.4) | 43 (18.2) | 50 (21.2) | 0.351 |
| No | 228 (63.5) | 119 (33.1) | 109 (30.4) | 143 (60.6) | 75 (31.8) | 68 (28.8) | ||
| Capsular invasion | ||||||||
| Yes | 253 (70.5) | 123 (34.3) | 130 (36.2) | 0.811 | 162 (68.6) | 83 (35.2) | 79 (33.5) | 0.575 |
| No | 106 (29.5) | 53 (14.8) | 53 (14.8) | 74 (31.4) | 35 (14.8) | 39 (16.5) | ||
| Nodular goiter | ||||||||
| Yes | 99 (27.6) | 50 (13.9) | 49 (13.6) | 0.729 | 66 (28) | 34 (14.4) | 32 (13.6) | 0.772 |
| No | 260 (72.4) | 126 (35.1) | 134 (37.3) | 170 (72) | 84 (35.6) | 86 (36.4) | ||
| Chronic thyroiditis | ||||||||
| Yes | 94 (26.2) | 40 (11.1) | 54 (15) | 0.144 | 63 (26.7) | 28 (11.9) | 35 (14.8) | 0.303 |
| No | 265 (73.8) | 136 (37.9) | 129 (35.9) | 173 (73.3) | 90 (38.1) | 83 (35.2) | ||
| Thyroid adenoma | ||||||||
| Yes | 5 (1.4) | 4 (1.1) | 1 (0.3) | 0.207 | 3 (1.3) | 2 (0.8) | 1 (0.4) | 1 |
| No | 354 (98.6) | 172 (47.9) | 182 (50.7) | 233 (98.7) | 116 (49.2) | 117 (49.6) | ||
| Variant subtype | ||||||||
| Classic | 261 (72.7) | 136 (37.9) | 125 (34.8) | 0.054 | 164 (69.5) | 84 (35.6) | 80 (33.9) | 0.432 |
| Follicular | 65 (18.1) | 30 (8.4) | 35 (9.7) | 48 (20.3) | 25 (10.6) | 23 (9.7) | ||
| Classic and follicular (multiple foci) | 33 (9.2) | 10 (2.8) | 23 (6.4) | 24 (10.2) | 9 (3.8) | 15 (6.4) | ||
| CLNM | ||||||||
| Yes | 166 (46.2) | 80 (22.3) | 86 (24) | 0.77 | 106 (44.9) | 49 (20.8) | 57 (24.2) | 0.295 |
| No | 193 (53.8) | 96 (26.7) | 97 (27) | 130 (55.1) | 69 (29.2) | 61 (25.8) | ||