Table 5.

Univariate and multivariate logistic regression analysis on UI level for the presence of CLNM in PTC patients

Urinary iodine status (μg/L)	Univariate			Multivariatec
	OR	95% CI	P value	OR	95% CI	P value
Total patientsa
≤ 99 (n = 102)	0.59	0.36–0.98	0.043	0.71	0.41–1.23	0.221
100–199 (n = 164)	Reference			Reference
≥ 200 (n = 93)	0.98	0.59–1.63	0.934	0.99	0.59–1.83	0.98
PTC ≥ 1 cma
≤ 99 (n = 39)	0.4	0.17–0.91	0.031	0.51	0.20–1.30	0.161
100–199 (n = 56)	Reference			Reference
≥ 200 (n = 30)	1.03	0.41–2.69	0.956	1.26	0.44–3.73	0.674
PTC < 1 cma
≤ 99 (n = 63)	0.7	0.36–1.33	0.281	0.73	0.35–1.48	0.381
100–199 (n = 108)	Reference			Reference
≥ 200 (n = 63)	0.98	0.52–1.85	0.96	1.09	0.55–2.15	0.815
Total patientsb
≤ 109 (n = 135)	0.44	0.26–0.72	0.001	0.53	0.31–0.91	0.021
110–189 (n = 120)	Reference			Reference
≥ 190 (n = 104)	0.68	0.40–1.15	0.154	0.71	0.41–1.29	0.281
PTC ≥ 1 cmb
≤ 109 (n = 50)	0.38	0.16–0.89	0.028	0.59	0.22–1.58	0.294
110–189 (n = 42)	Reference			Reference
≥ 190 (n = 33)	0.9	0.34–2.40	0.826	1.33	0.45–4.06	0.608
PTC < 1 cmb
≤ 109 (n = 85)	0.44	0.23–0.83	0.012	0.43	0.21–0.87	0.019
110–189 (n = 78)	Reference			Reference
≥ 190 (n = 71)	0.61	0.32–1.18	0.143	0.65	0.32–1.33	0.242

^aIodine insufficient, adequate, and above requirements (including excessive) were defined as ≤ 99 μg/L, 100–199 μg/L, and ≥ 200 μg/L

^bIodine insufficient, adequate, and above requirements (including excessive) were defined as ≤ 109 μg/L, 110–189 μg/L, and ≥ 190 μg/L

^cAdjusted for age, sex, multifocality, tumor size, and variant subtype