| Methods |
Randomised controlled trial with concurrent eligible patients outside of the RCT. The non‐RCT patients were not in the trial because they refused randomisation. Patients undergoing outpatient colonoscopy. No losses to follow up. |
| Data |
Characteristics of the non‐randomised patients compared to RCT patients who received the same treatment. RCT patients given intravenous were on average 49 (25 to 75) years, 29 male and 17 female. Non‐RCT patients given intravenous were on average 52 (18 to 82) years, 29 male and 59 female. |
| Comparisons |
Two RCT arms, the control group patients were compared with the non‐randomised patients who received similar treatment. Experimental: self‐administered inhaled nitrous oxide (Entonox: 50% nitrous oxide, 50% oxygen). Control: intravenous sedation/analgesia (Midazolam and Meperidine). |
| Outcomes |
Outcomes were assessed in all patients. The volunteers were followed for a minimum of 30 minutes after colonoscopy. Main outcome was # of adverse events. |
| Notes |
The experimental treatment was less effective than control. |
