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. 2021 Jul 6;125(27):7368–7379. doi: 10.1021/acs.jpcb.1c03639

Figure 6.

Figure 6

(Left) One-dimensional potential of mean force (1D PMF) of CR3022–RBD (black curve) and 4A8–NTD (red curve). Results were obtained by applying the WHAM analysis for 750 ns REX-US simulations. (Right) KD curves as a function of r* corresponding to the change in the total free monomer concentration from eq 5. Pb and KD were determined at r* = 11 nm.